Arsenal are level on points with PSG at the top of the group, and their manager wants a victory to ensure a favourable draw in the last 16.
A win on Wednesday would secure top spot with one game to play, as it would leave Wenger's team three points clear of PSG and with a better head-to-head record. The winners will be drawn against a runner-up from another group in the next round.
Arsenal drew 1-1 away to PSG on 13 September, and Wenger added: "We have done the job in a convincing way.
"Now, we have to finish the job at home. We played a draw there and now it is down to us to win the game."
'I have never forced anyone to play'
Arsenal are unbeaten in 17 games, are three points off the top of the Premier League while they have breezed through to the next stage in Europe.
Yet Wenger was not all buoyant at his news conference on Tuesday.
The 67-year-old angrily denied suggestions he was gambling on the fitness of Alexis Sanchez after the forward played the whole game on Saturday despite injuring a hamstring while on international duty with Chile."I've never demanded anyone should be injected to play," added Wenger.
"He had a bit of tightness in his hamstring, but he was checked before the game.
"If a player is 100%, I make a decision. But the suggestions I have forced him to play are wrong, completely wrong."
Sanchez, 27, has scored eight goals in 16 club appearances this season. Wenger would not confirm if the Chile international would start against PSG.
Two players who will definitely not be involved because of injury are Spain pair Santi Cazorla, 31, and Hector Bellerin, 21.
Defender Bellerin, who has just signed a new long-term deal, misses out with an ankle injury while midfielder Cazorla has an Achilles problem.
Another PSG defeat on English soil?
PSG have won only one of their eight away games against English opposition in all competitions (D3 L4).
The French club are yet to beat Arsenal in European competition (D2 L1).
PSG have failed to keep a clean sheet in their last nine competitive games against English clubs.
Arsenal have won their two home games in this season's Champions League, scoring eight goals and conceding none.
Since their return to the Champions League in 2012/13, PSG have won 20 of their 28 group games.
Arsenal have made it past the group stages for the 14th consecutive season but have been knocked out at the last 16 stage in the last six campaigns.
Mesut Ozil has scored four and assisted two of Arsenal's last eight Champions League goals.
Edinson Cavani's goal after 42 seconds against Arsenal in September is the fastest in the Champions League this season. In fact, all three goals conceded by Arsenal in this season's competition have come in the opening 15 minutes.